pentobarbital will lower the level or result of vinorelbine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.
pentobarbital will minimize the extent or influence of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Solid CYP3A4 inducers may well lessen midostaurin concentrations leading to lowered efficacy.
pentobarbital will lower the extent or impact of maraviroc by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the extent or influence of darifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or impact of fentanyl intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Coadministration of fentanyl with CYP3A4 inducers could lead into a reduce in fentanyl plasma concentrations, insufficient efficacy or, possibly, progress of the withdrawal syndrome in a affected person who's got made physical dependence to fentanyl.
pentobarbital will lessen the level or effect of pitolisant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Pitolisant exposure is reduced by 50% if coadministered with strong CYP3A4 inducers.
pentobarbital will lessen the extent or influence of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will minimize the extent or impact of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Observe Closely (1)pentobarbital will improve the level or outcome of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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pentobarbital will enhance the level or outcome of ivosidenib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of ivosidenib with potent CYP3A4 inducers lessened ivosidenib plasma concentrations.
pentobarbital will reduce the level or influence of temsirolimus website by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Contraindicated (one)pentobarbital will lower the level or effect of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or impact of tamoxifen by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.